Role of miR-199b-5p in regulating angiogenesis in mouse myocardial microvascular endothelial cells through HSF1/VEGF pathway

Highlights • miR-199b-5p can regulate MMVEC proliferation and tubule formation. • miR-199b-5p can regulate protein expression of HSF1. • Role of miR-199b-5p regulating MMVEC proliferation and tubule formation.

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Bibliographic Details
Published inEnvironmental toxicology and pharmacology Vol. 47; pp. 142 - 148
Main Authors Du, Peizhao, Dai, Fangjie, Chang, Yaowei, Wei, Chunyan, Yan, Jing, Li, Jiming, Liu, Xuebo
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.10.2016
Elsevier Science Ltd
Subjects
Angiogenesis
Blood vessels
Cell culture
Cell proliferation
Cells
Control
Emergency
Endothelial Cells
Endothelium
Heat shock
Heat shock factors
Heat shock proteins
HSF1
HSF1 protein
Microvasculature
miR-199b-5p
mRNA
Myocardial microvascular endothelial cells
Polymerase chain reaction
Ribonucleic acid
RNA
Rodents
Vascular endothelial growth factor
VEGF
Western blotting
Angiogenesis
miR-199b-5p
Myocardial microvascular endothelial cells
VEGF
HSF1
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Summary:Highlights • miR-199b-5p can regulate MMVEC proliferation and tubule formation. • miR-199b-5p can regulate protein expression of HSF1. • Role of miR-199b-5p regulating MMVEC proliferation and tubule formation.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2016.09.007