Upper eyelid retraction disclosed after edrophonium chloride administration in a patient with Graves' orbitopathy and myasthenia gravis

Patients with Graves' orbitopathy have a higher probability of myasthenia gravis than does the normal population. Overlapping clinical features cause diagnostic confusion in such a situation. We herein report a patient with Graves' orbitopathy and myasthenia gravis (GO-MG) with normal left...

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Bibliographic Details
Published inClinical ophthalmology (Auckland, N.Z.) Vol. 6; pp. 807 - 810
Main Authors Kang, Hyera, Takahashi, Yasuhiro, Iwaki, Masayoshi, Asamura, Shinichi, Kakizaki, Hirohiko
Format Journal Article
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2012
Taylor & Francis Ltd
Dove Press
Dove Medical Press
Subjects
Case Report
Diagnosis
Edrophonium
edrophonium chloride
eyelid retraction
Graves' orbitopathy
Myasthenia gravis
Ophthalmology
myasthenia gravis
edrophonium chloride
eyelid retraction
Graves’ orbitopathy
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Summary:Patients with Graves' orbitopathy have a higher probability of myasthenia gravis than does the normal population. Overlapping clinical features cause diagnostic confusion in such a situation. We herein report a patient with Graves' orbitopathy and myasthenia gravis (GO-MG) with normal left eyelid height, but in whom upper eyelid retraction was shown after edrophonium chloride administration. Upper eyelid retraction in GO-MG is occasionally masked by a myasthenia effect. The upper eyelid height must be carefully monitored in patients with Graves' orbitopathy to detect the presence of concomitant myasthenia gravis.
ISSN:1177-5483
1177-5467
1177-5483
DOI:10.2147/OPTH.S29408