TOR signaling in plants: conservation and innovation

Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that plays a central role in both plants and animals, despite their distinct developmental programs and survival strategies. Indeed, TOR integrates nutrient, energy, hormone, growth factor and environmental inputs to control pro...

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Published inDevelopment (Cambridge) Vol. 145; no. 13; p. dev160887
Main Authors Shi, Lin, Wu, Yue, Sheen, Jen
Format Journal Article
LanguageEnglish
Published England The Company of Biologists Ltd 01.07.2018
Subjects
Cell division
Kinases
Plant Development - physiology
Plant Proteins - genetics
Plant Proteins - metabolism
Plants - genetics
Plants - metabolism
Primer
Progenitor cells
Protein kinase
Rapamycin
Signal Transduction - physiology
TOR protein
TOR Serine-Threonine Kinases - genetics
TOR Serine-Threonine Kinases - metabolism
Target of rapamycin protein kinase
Stem cell niche
Metabolism reprogramming
Nutrient signaling
Cell cycle regulation
Meristem
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Summary:Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that plays a central role in both plants and animals, despite their distinct developmental programs and survival strategies. Indeed, TOR integrates nutrient, energy, hormone, growth factor and environmental inputs to control proliferation, growth and metabolism in diverse multicellular organisms. Here, we compare the molecular composition, upstream regulators and downstream signaling relays of TOR complexes in plants and animals. We also explore and discuss the pivotal functions of TOR signaling in basic cellular processes, such as translation, cell division and stem/progenitor cell regulation during plant development.
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These authors contributed equally to this work
ISSN:0950-1991
1477-9129
1477-9129
DOI:10.1242/dev.160887