Rectal and Vaginal Eradication of Streptococcus agalactiae (GBS) in Pregnant Women by Using Lactobacillus salivarius CECT 9145, A Target-specific Probiotic Strain

• Published in: Nutrients Vol. 11; no. 4; p. 810
• Main Authors: Martín, Virginia, Cárdenas, Nivia, Ocaña, Sara, Marín, María, Arroyo, Rebeca, Beltrán, David, Badiola, Carlos, Fernández, Leónides, Rodríguez, Juan M
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 10.04.2019; MDPI
• Subjects: Adult; Antibiotics; Antiinfectives and antibacterials; Antimicrobial activity; Bacteriocins; Colonization; Epidemiology; Female; Food safety; GBS; Health care; Humans; Infections; Infectious diseases; Intestine; Lactation; Lactobacilli; Lactobacillus salivarius; Mastitis; Microbiomes; Microbiota; Microorganisms; Neonates; Oral administration; Organic acids; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious - microbiology; Pregnancy Complications, Infectious - therapy; probiotic; Probiotics; Probiotics - therapeutic use; Rectum; Rectum - microbiology; Sepsis; Streptococcal Infections - microbiology; Streptococcal Infections - therapy; Streptococcus agalactiae; Streptococcus agalactiae - drug effects; Streptococcus infections; Treatment Outcome; Vagina; Vagina - microbiology; Womens health; United Kingdom > UK; France; United States > US; Spain; GBS; probiotic; Streptococcus agalactiae; Lactobacillus salivarius; pregnancy

(Group B Streptococci, GBS) can cause severe neonatal sepsis. The recto-vaginal GBS screening of pregnant women and intrapartum antibiotic prophylaxis (IAP) to positive ones is one of the main preventive options. However, such a strategy has some limitations and there is a need for alternative appro...