Performance of a new interference-resistant glucose meter

• Published in: Clinical biochemistry Vol. 43; no. 1; pp. 186 - 192
• Main Authors: Vanavanan, Somlak, Santanirand, Pitak, Chaichanajarernkul, Upsorn, Chittamma, Anchalee, DuBois, Jeffrey A., Shirey, Terry, Heinz, Mark
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 2010; Elsevier
• Subjects: Acetaminophen - analysis; Ascorbic Acid - analysis; Biological and medical sciences; Biosensing Techniques - instrumentation; Biosensing Techniques - methods; Blood Chemical Analysis - instrumentation; Blood Chemical Analysis - methods; Blood Chemical Analysis - standards; Blood Glucose - analysis; Blood Glucose Self-Monitoring - instrumentation; Blood Glucose Self-Monitoring - methods; Blood Glucose Self-Monitoring - standards; Glucose meter; Humans; Interference-resistant glucose meter; Investigative techniques, diagnostic techniques (general aspects); Maltose - analysis; Medical sciences; Miscellaneous. Technology; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; POCT; Point-of-Care Systems; Point-of-Care-Testing; Reagent Strips; Reference Values; Reproducibility of Results; Self-monitoring of blood glucose (SMBG); Sensitivity and Specificity; Self-monitoring of blood glucose (SMBG); Point-of-Care-Testing; Interference-resistant glucose meter; POCT; Glucose meter; Performance evaluation; Human; Ascorbic acid; Glucometer; Antimigrainous agent; Vitamin; Hematocrit; Interference; Maltose; Paracetamol; Analgesic; Technology; Reagent strip; Point of care testing; Antipyretic; Self control; Glycemia; Quantitative analysis
• ISSN: 0009-9120; 1873-2933
• DOI: 10.1016/j.clinbiochem.2009.09.010

Glucose meters are widely used in self and hospital monitoring of blood glucose. We examined the analytical performance of a StatStrip glucose monitoring system. Linearity, % recovery and within-run imprecision were studied using glucose-spiked whole blood. A total of 120 heparinized samples were used in method comparison using a plasma hexokinase on the Dimension RxL MAX analyzer as the comparison method. Common interferences were tested on the StatStrip, Accu-Chek Advantage and the MediSense Optium glucose meters at low, middle and high glucose levels. The StatStrip assay showed excellent linearity and recovery. The coefficient of variations for imprecision were < 5%. This meter correlated well with the comparison method ( y = 0.994X + 0.03; r = 0.995, S y/x = 0.05 mmol/L, bias = − 0.01 mmol/L). Of the three meters tested, only the StatStrip showed interference < 10% for all spiked levels of acetaminophen, ascorbic acid, maltose and hematocrit at three levels of glucose tested. The StatStrip meter showed good performance and is suitable for point-of-care hospital glucose testing.