Rupestines F-M, New Guaipyridine Sesquiterpene Alkaloids from Artemisia rupestris

Eight new guaipyridine sesquiterpene alkaloids, rupestines F-M (1-8) were isolated from the leaves of Artemisia rupestris and their structures were elucidated on the basis of 2D-NMR data. The absolute configurations of 1-8 have been assigned by comparison of their experimental and calculated circula...

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Bibliographic Details
Published inChemical & pharmaceutical bulletin Vol. 60; no. 2; pp. 213 - 218
Main Authors He, Fei, Nugroho, Alfarius Eko, Wong, Chin Piow, Hirasawa, Yusuke, Shirota, Osamu, Morita, Hiroshi, Aisa, Haji Akber
Format Journal Article
LanguageEnglish
Published TOKYO The Pharmaceutical Society of Japan 2012
Pharmaceutical Soc Japan
Japan Science and Technology Agency
Subjects
absolute configuration
Alkaloids - chemistry
Artemisia - chemistry
Artemisia rupestris
Chemistry
Chemistry, Medicinal
Chemistry, Multidisciplinary
Circular Dichroism
Computer Simulation
guaipyridine sesquiterpene alkaloid
Life Sciences & Biomedicine
Magnetic Resonance Spectroscopy
Molecular Structure
Pharmacology & Pharmacy
Physical Sciences
Plant Leaves - chemistry
Pyrimidines - chemistry
rupestine
Science & Technology
Sesquiterpenes - chemistry
DENSITY
Artemisia rupestris
MECHANICS
rupestine
MMFF94
circular dichroism
PARAMETERS
guaipyridine sesquiterpene alkaloid
absolute configuration
MOLECULAR-FORCE FIELD
VAN-DER-WAALS
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Summary:Eight new guaipyridine sesquiterpene alkaloids, rupestines F-M (1-8) were isolated from the leaves of Artemisia rupestris and their structures were elucidated on the basis of 2D-NMR data. The absolute configurations of 1-8 have been assigned by comparison of their experimental and calculated circular dichroism (CD) spectra.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.60.213