Microsatellite variation in Drosophila melanogaster and Drosophila simulans: a reciprocal test of the ascertainment bias hypothesis

• Published in: Molecular biology and evolution Vol. 15; no. 12; pp. 1620 - 1636
• Main Authors: Hutter, C M, Schug, M D, Aquadro, C F
• Format: Journal Article
• Language: English
• Published: United States 01.12.1998
• Subjects: Animals; Base Sequence; Chromosome Mapping; DNA Primers; Drosophila - genetics; Drosophila melanogaster; Drosophila melanogaster - genetics; Drosophila simulans; Genetic Markers; Genetic Variation; Genomic Library; Heterozygote; Microsatellite Repeats; Models, Genetic; Models, Statistical; Polymerase Chain Reaction; Regression Analysis

Interspecific comparisons of microsatellite loci have repeatedly shown that the loci are longer and more variable in the species from which they are derived (the focal species) than are homologous loci in other (nonfocal) species. There is debate as to whether this is due to directional evolution or...