Graphene-based biosensors: methods, analysis and future perspectives

• Published in: IET circuits, devices & systems Vol. 9; no. 6; pp. 434 - 445
• Main Authors: Celik, Numan, Balachandran, Wamadeva, Manivannan, Nadarajah
• Format: Journal Article
• Language: English
• Published: Stevenage The Institution of Engineering and Technology 01.11.2015; John Wiley & Sons, Inc
• Subjects: Algorithms; Biomedical engineering; Biomedical materials; biomedicine; Biosensors; cancer; cancer therapy; Carbon; Chemical properties; Chemical sensors; cholesterol sensing; Composite materials; Detection; Dimensional analysis; DNA; DNA sensing; drug delivery; drug delivery systems; electrical conductivity; electrical properties; Electrical resistivity; electrochemical sensors; Electron mobility; Electronics; gene delivery; gene therapy; glucose sensing; Graphene; graphene-based biosensors; Graphite; Haemoglobin; Heat conductivity; High temperature; Nanomaterials; Nanostructure; physical properties; proteins; Sensors; single layer two-dimensional structure nanomaterial; Special Issue: Graphene Electronics: Part 2; surface area; Thermal conductivity; Tissue engineering; drug delivery systems; physical properties; tissue engineering; C; chemical properties; drug delivery; surface area; cancer therapy; haemoglobin; proteins; electron mobility; electrical properties; cholesterol sensing; gene therapy; biosensors; biomedicine; DNA sensing; gene delivery; graphene-based biosensors; electrochemical sensors; DNA; single layer two-dimensional structure nanomaterial; cancer; thermal conductivity; electrical conductivity; glucose sensing
• ISSN: 1751-858X; 1751-8598; 1751-8598
• DOI: 10.1049/iet-cds.2015.0235

Graphene (GN), a single layer two-dimensional structure nanomaterial, exhibits exceptional physical, electrical and chemical properties that lead to many applications from electronics to biomedicine. The unique parameters of GN, notably its considerable electron mobility, thermal conductivity, high surface area and electrical conductivity, are bringing heightened attention into biomedical applications. This study assesses the recent advances in GN-based biosensors and its derivatives in different areas to focus on glucose sensing, DNA sensing, drug and gene delivery, cancer therapy and other related biomedical applications (electrochemical sensors, tissue engineering, haemoglobin and cholesterol sensing), together with a brief discussion on challenges and future perspectives in this rapidly developing field.