Enhancing current human immunodeficiency virus/hepatitis B and human immunodeficiency virus/hepatitis C virus co-infection management

[...]screening HIV in HBV or HCV patients provides an opportunity to diagnose and manage the infection at an earlier stage. [...]routine HIV screening is strongly recommended among newly diagnosed HBV and HCV patients. The higher risk of all-cause death and non-liver-related cancers in HIV/HCV co-in...

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Published inChinese medical journal Vol. 133; no. 23; pp. 2890 - 2891
Main Authors Huang, Zhan-Lian, Chen, Da-Biao, Gao, Zhi-Liang, Lin, Bing-Liang
Format Journal Article
LanguageEnglish
Published China Lippincott Williams & Wilkins 05.12.2020
Lippincott Williams & Wilkins Ovid Technologies
Department of Infectious Diseases, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510630, China
Wolters Kluwer
Subjects
Coinfection - drug therapy
Enzymes
Hepacivirus
Hepatitis B
Hepatitis B - drug therapy
Hepatitis C
Hepatitis C - drug therapy
HIV
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Infections
Infectious diseases
Liver diseases
Mathematical models
Mortality
Prevalence
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Summary:[...]screening HIV in HBV or HCV patients provides an opportunity to diagnose and manage the infection at an earlier stage. [...]routine HIV screening is strongly recommended among newly diagnosed HBV and HCV patients. The higher risk of all-cause death and non-liver-related cancers in HIV/HCV co-infected patients can be explained by chronic inflammation and immune system dysregulation due to HIV infection and high-risk behaviors such as tobacco smoking and alcohol consumption in the co-infected subjects. [4] PLWH co-infected with HBV or HCV are at markedly increased risk for ESLD compared with those monoinfected by HIV. Since the introduction of combination ART, morbidity, and mortality were significantly reduced in PLWH.
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ISSN:0366-6999
2542-5641
2542-5641
DOI:10.1097/CM9.0000000000001149