Impact of Emergency Surgery in the Outcome of Rectal and Left Colon Carcinoma

• Published in: World journal of surgery Vol. 29; no. 11; pp. 1458 - 1464
• Main Authors: Coco, Claudio, Verbo, Alessandro, Manno, Alberto, Mattana, Claudio, Covino, Marcello, Pedretti, Giorgio, Petito, Luigi, Rizzo, Gianluca, Picciocchi, Aurelio
• Format: Journal Article
• Language: English
• Published: New York Springer‐Verlag 01.11.2005; Springer; Springer Nature B.V
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Chronic Obstructive Pulmonary Disease; Colonic Neoplasms - epidemiology; Colonic Neoplasms - mortality; Colonic Neoplasms - surgery; Comorbidity; Digestive System Surgical Procedures; Emergency Group; Emergency Presentation; Emergency Procedure; Emergency Treatment; Female; Gastroenterology. Liver. Pancreas. Abdomen; General aspects; Humans; Length of Stay; Male; Mechanical Bowel Preparation; Medical sciences; Middle Aged; Multivariate Analysis; Rectal Neoplasms - epidemiology; Rectal Neoplasms - mortality; Rectal Neoplasms - surgery; Retrospective Studies; Sigmoid Neoplasms - surgery; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Treatment Outcome; Tumors; Rectal disease; Prognosis; Malignant tumor; Colonic disease; Medicine; Treatment; Surgery; Digestive diseases; Intestinal disease; Evolution; Emergency; Left colon; Colon carcinoma; Rectal carcinoma
• ISSN: 0364-2313; 1432-2323
• DOI: 10.1007/s00268-005-7826-9

The negative results in terms of morbidity, mortality and survival among emergency treated patients affected by colorectal cancer are well known. The specific contribution of emergency surgery to adverse outcome is not clear because of the presence in all series of other possible determinants of a poor prognosis. We used a case‐control study design to compare a group of 50 patients operated on for cancer of the rectum and left colon presented as emergencies in our department during the last 14 years, and an equal number of patients who underwent elective procedures during the same period. All records of these patients were reviewed and matched for age, stage, tumor location, and medical comorbidities (coronaropathy, diabetes mellitus, cerebral vascular deficiency, chronic obstructive pulmonary disease). Outcome measures included length of hospital stay, morbidity, mortality, and actuarial 5‐year survival. Univariate and multivariate analysis of factors potentially influencing survival was performed on the entire population of 100 patients. Age, tumor location, stage of disease, and medical comorbidities were well matched by intent of the study design. Overall surgical morbidity (44% versus 12% P = 0.0004), length of hospital stay (16, 64 versus 10, 97 days P = 0.0026) and postoperative mortality (4% versus 0% P = 0.4949) resulted higher in the emergency group. Actuarial overall 5‐year survival was not different between the two groups. The only variables independently predictive of survival in multivariate analysis were age and rectal location of the tumor. Postoperative surgical mortality and long‐term survival appear not to be influenced by emergency presentation of colorectal cancer; the negative impact of the emergency procedures is confined to the immediate postoperative period and is probably connected to the acute medical pathology often presented by patients in emergency situations. Dealing with this kind of patient’s accurate preoperative assessment and solution of acute medical pathologies before surgical treatment are mandatory.