Linear Superposition Electrical Impedance Tomography Imaging With Multiple Electrical/Biopsy Probes

• Published in: IEEE transactions on biomedical engineering Vol. 56; no. 5; pp. 1465 - 1472
• Main Authors: Ivorra, Antoni, Shini $^\ast$, Mohanad, Rubinsky, Boris
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.05.2009; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Agar; Biopsy; Biopsy, Needle; Conductivity; Electric Impedance; electrical impedance tomography (EIT); Equations; Equipment Design; Humans; Image Interpretation, Computer-Assisted - methods; Image Processing, Computer-Assisted - methods; Image sampling; Impedance; Medical diagnosis; minimally invasive medical imaging; Needles; Phantoms, Imaging; Probes; Tomography; Tomography - instrumentation; Tomography - methods; Ultrasonic imaging; Ultrasonography
• ISSN: 0018-9294; 1558-2531
• DOI: 10.1109/TBME.2009.2013821

In medical diagnostics, tissue is often examined with multiple discrete biopsies taken under ultrasound placement. In a previous theoretical study, we have suggested that the linear nature of the equations used in electrical impedance tomography (EIT) can be employed with the conventional practice of biopsy sampling to produce an image of the tissue between the biopsy samplings. Specifically, the biopsy probes can be used to record EIT-type electrical data during the discrete tissue sampling. The location of the discrete biopsy needle insertions available from the ultrasound placement of the probes can be combined with the electrical measurement data and used with linear superposition to produce a complete EIT image of the tissue between the sampled sites. In this study, we explore the concept experimentally using gel phantoms to simulate tissue and heterogeneities in the tissue. The experiments are performed in 2-D and 3-D configurations, and data are taken discretely, one at a time, through single electrical probe insertions. In the 2-D configuration, we were able to produce images of reasonable quality for heterogeneities with a diameter larger than 3 mm (conductivity ratio 1:5) and with relative conductivity differences above 50% (diameter 5 mm).