Oncogenic osteomalacia: A reversible metabolic bone disorder

The partial response seen in one of the patients in the series may well be due to coexisting hypovitaminosis D. The resolution of these biochemical and bone abnormalities following tumor removal supports the notion of the presence of a circulating factor (phosphatonin) secreted by the tumor. In a sm...

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Bibliographic Details
Published inIndian journal of orthopaedics Vol. 44; no. 4; pp. 361 - 362
Main Author Dhanwal, Dinesh Kumar
Format Journal Article
LanguageEnglish
Published Switzerland Medknow Publications and Media Pvt. Ltd 01.10.2010
Medknow Publications & Media Pvt. Ltd
Medknow Publications
Subjects
Fibroblast growth factors
Pathogenesis
Phosphatases
Phosphates
Tumors
Vitamin D
Vitamin deficiency
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Summary:The partial response seen in one of the patients in the series may well be due to coexisting hypovitaminosis D. The resolution of these biochemical and bone abnormalities following tumor removal supports the notion of the presence of a circulating factor (phosphatonin) secreted by the tumor. In a small group of patients, despite the use of modern imaging modalities, a tumor is not detected, and these patients should be treated with the vitamin D metabolite calcitriol and oral phosphate salt.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0019-5413
1998-3727
DOI:10.4103/0019-5413.67124