Nanoenabled Bioseparations: Current Developments and Future Prospects

• Published in: BioMed research international Vol. 2019; no. 2019; pp. 1 - 15
• Main Authors: Bakowsky, Udo, Brüßler, Jana, Alawak, Mohamad, Fahmy, Sherif Ashraf, El-Sayed, Mayyada M. H.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2019; Hindawi; Hindawi Limited
• Subjects: Amino acids; Amino Acids - chemistry; Amino Acids - isolation & purification; Binding sites; Biomolecules; Biotechnology; Carbon; Carbon nanotubes; Cellulose acetate; Chromatography; Enzymes - chemistry; Enzymes - isolation & purification; Fabrication; Magnetic fields; Magnetite Nanoparticles - chemistry; Membranes; Membranes, Artificial; Nanofibers; Nanofibers - chemistry; Nanomaterials; Nanoparticles; Nanotechnology; Nanotubes; Nanotubes, Carbon - chemistry; Nucleic acids; Nucleic Acids - chemistry; Nucleic Acids - isolation & purification; Oxidation; Performance evaluation; Polymers; Proteins; Proteins - chemistry; Proteins - isolation & purification; Review; Science; State-of-the-art reviews; Synthesis
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2019/4983291

The use of nanomaterials in bioseparations has been recently introduced to overcome the drawbacks of the conventional methods. Different forms of nanomaterials, particularly magnetic nanoparticles (MNPs), carbon nanotubes (CNTs), casted nanoporous membranes, and electrospun nanofiber membranes were utilized in biological separation for the aim of production of different biomolecules such as proteins, amino acids, nucleic acids, and enzymes. This paper critically reviews the state-of-the-art efforts undertaken in this regard, with emphasis on the synthesis and performance evaluation of each nanoform. Challenges and future prospects in developing nanoenabled bioseparations are also discussed, for the purpose of highlighting potential advances in the synthesis and fabrication of novel nanomaterials as well as in the design of efficient nanoenabled processes for separating a wide spectrum of biomolecules.