Analgesic activity of some Indian medicinal plants

• Published in: Journal of ethnopharmacology Vol. 106; no. 3; pp. 425 - 428
• Main Authors: Malairajan, P., Geetha Gopalakrishnan, Narasimhan, S., Jessi Kala Veni, K.
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 19.07.2006; Elsevier
• Subjects: Analgesic; analgesic effect; Analgesics - administration & dosage; Analgesics - pharmacology; Analgesics - therapeutic use; Animals; bark; Biological and medical sciences; Bougainvilla spectabilis; Bougainvillea; Bougainvillea spectabilis; chemical constituents of plants; Dose-Response Relationship, Drug; ethnobotany; Female; Ficus glomerata; Ficus racemosa; General pharmacology; heartwood; herbal medicines; Hot Temperature; India; Injections, Intraperitoneal; leaves; Male; Medical sciences; medicinal plants; medicinal properties; Medicine, Traditional; Mice; Pain - prevention & control; Pain Measurement - drug effects; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Phytotherapy; Plant Bark; plant extracts; Plant Extracts - administration & dosage; Plant Extracts - pharmacology; Plant Extracts - therapeutic use; Plant Leaves; Plants, Medicinal; Polyalthia longifolia; Rats; Rats, Wistar; Sida acuta; Stylosanthes; Stylosanthes fruticosa; Toona ciliata; traditional medicine; Wood; India; Sida acuta; Ficus glomerata; Stylosanthes fruticosa; Analgesic; Toona ciliata; Bougainvilla spectabilis; Polyalthia longifolia; Protozoa; Pharmacognosy; Moraceae; Medicinal plant; Stylosanthes; Leguminosae; Ficus; Dicotyledones; Angiospermae; Plant origin; Spermatophyta; Ciliata; Annonaceae
• ISSN: 0378-8741; 1872-7573
• DOI: 10.1016/j.jep.2006.03.015

In the present study of some of the Indian medicinal plants Sida acuta whole plant (Malvaeae), Stylosanthes fruticosa (whole plant) (Papilionaceae), Toona ciliata (heart wood) (Meliaceao), Bougainvilla spectabilis (leaves) (Nyctaginaceae), Ficus glomerata (bark, leaves) (Moraceae) and Polyalthia longifolia (leaves) (Annonaceae). The different plants were used in folklore medicine in the treatment of toothache and strengthening of gums, anthelmintic, kidney diseases, analgesic, anti-inflammatory, hepatoprotective, antihyperglycaemic, antihyperglycaemic and anticancer. The extract was prepared using powdered material with ethanol, concentrated under vacuo and were evaluated for analgesic activity by analgesiometer at three dose level (100, 300 and 500 mg/kg). Analgesic activity was significant with Toona ciliata (heart wood) ethanolic extract when compared with other extracts and its activity was confirmed by tail immersion method.