Semaphorin3A: A potential therapeutic tool in immune-mediated diseases

The significance of semaphorin3A (sema3A) in regulating immune-mediated inflammation is widely reported. There are multiple mechanisms involved in the process of sema3A-mediated regulation. One of them is the ability of sema3A to maintain a sufficient regulation of both T-cell and B-cell activation....

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Published inEuropean journal of rheumatology Vol. 5; no. 1; pp. 58 - 61
Main Authors Vadasz, Zahava, Toubi, Elias
Format Journal Article
LanguageEnglish
Published Turkey AVES 01.03.2018
Medical Research and Education Association
Subjects
Atopic dermatitis
Care and treatment
Health aspects
Immune response regulation
Inflammation
Invited Review
Rheumatic diseases
Semaphorins
immune mediated diseases
Semaphorin 3A
atopic diseases
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Summary:The significance of semaphorin3A (sema3A) in regulating immune-mediated inflammation is widely reported. There are multiple mechanisms involved in the process of sema3A-mediated regulation. One of them is the ability of sema3A to maintain a sufficient regulation of both T-cell and B-cell activation. Because it is involved in the pathogenesis of many autoimmune, infectious, and malignant diseases, sema3A turns to be a promising therapeutic tool to be studied and applied in these diseases.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:2147-9720
2148-4279
DOI:10.5152/eurjrheum.2017.17076