Progressive multifocal leukoencephalopathy in a HIV/HTLV co-infected patient

• Published in: Journal of the neurological sciences Vol. 325; no. 1; pp. 174 - 175
• Main Authors: Santos, Edwiges Motta, Silva, Marcus Tulius T, Lima, Marco Antonio
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 15.02.2013; Elsevier
• Subjects: Adult; Biological and medical sciences; CD4 antigen; Coinfection - complications; Coinfection - diagnosis; HIV; HIV Infections - complications; HIV Infections - diagnosis; HTLV-1; HTLV-I Infections - complications; HTLV-I Infections - diagnosis; Human immunodeficiency virus; Human T-lymphotropic virus 1; Human viral diseases; Humans; Immune status; Infection; Infectious diseases; JC virus; Leukoencephalopathy; Leukoencephalopathy, Progressive Multifocal - complications; Leukoencephalopathy, Progressive Multifocal - diagnosis; Lymphocytes T; Male; Medical sciences; Neurology; Progressive multifocal leukoencephalopathy; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; HTLV-1; HIV; JC virus; Leukoencephalopathy; Immunopathology; Nervous system diseases; Polyomavirus; AIDS; Papovaviridae; Immune deficiency; Inflammatory disease; Cerebral disorder; Progressive multifocal leukoencephalopathy; Infection; Virus; Viral disease; Central nervous system disease; Slow virus
• ISSN: 0022-510X; 1878-5883
• DOI: 10.1016/j.jns.2012.12.010

Abstract Many HIV infected patients are at risk for HTLV-I co-infection worldwide. These patients exhibit abnormally high CD4 + T lymphocyte counts that are not a reliable parameter of the immune status. We report a HIV/HTLV co-infected patient who developed progressive multifocal leukoencephalopathy despite of a high CD4 + T lymphocyte count emphasizing that this situation can be observed in regions around the world where HTLV-I infection is prevalent.