Sulfated Zirconia as an Efficient Catalyst for Sulfonylamidomethylation of Benzylsulfonamides and 2-Phenylethanesulfonamides: Effect of Catalyst Thermal Treatment

• Published in: Catalysis letters Vol. 138; no. 3-4; pp. 180 - 186
• Main Authors: Sasiambarrena, Leandro D, Mendez, Leticia J, Ocsachoque, Marco A, Cánepa, Alicia S, Bravo, Rodolfo D, González, M. Gloria
• Format: Journal Article
• Language: English
• Published: Boston Boston : Springer US 01.09.2010; Springer US; Springer; Springer Nature B.V
• Subjects: 2,3-Benzothiazine 2,2-dioxides; 2-Phenylethanesulfonamides; 3,2-Benzothiazepine 3,3-dioxides; Antifungal agents; Benzylsulfonamides; Catalysis; Catalysts; Catalytic activity; Chemical synthesis; Chemistry; Chemistry and Materials Science; Enzyme inhibitors; Exact sciences and technology; General and physical chemistry; Heat treatment; Industrial Chemistry/Chemical Engineering; Organometallic Chemistry; Physical Chemistry; Resveratrol; Selectivity; Sulfated zirconia; Sulfates; Sulfonylamidomethylation; Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry; Zirconium; Zirconium dioxide; Zirconium oxide; 3,2-Benzothiazepine 3,3-dioxides; Sulfonylamidomethylation; 2-Phenylethanesulfonamides; 2,3-Benzothiazine 2,2-dioxides; Benzylsulfonamides; Sulfated zirconia; Binary compound; Catalytic reaction; Heat treatment; Transition element compounds; Selectivity; Zirconia; Heterogeneous catalysis; Synthesis; Catalyst
• ISSN: 1011-372X; 1572-879X
• DOI: 10.1007/s10562-010-0389-x

The synthesis of 3,4-dihydro-1H-2,3-benzothiazine 2,2-dioxides and 1,2,4,5-tetrahydro-3,2-benzothiazepine 3,3-dioxides is studied using sulfated zirconia as catalyst. The sulfated zirconia calcined at 550 °C achieved a high selectivity which is attributed to the formation of a tetragonal phase. In addition, the catalyst can be reused up to three times without loss of its catalytic activity. Graphical Abstract [graphic removed]