Bacteremia Caused by Kalamiella piersonii Found in an Infant During the Course of Gastrointestinal Food Allergy

• Published in: Infection and drug resistance Vol. 16; pp. 2647 - 2651
• Main Authors: Sada, Jun, Hirai, Jun, Ota, Koki, Numoto, Shingo, Honma, Hitoshi, Mori, Nobuaki, Sakanashi, Daisuke, Mikamo, Hiroshige, Okumura, Akihisa
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 31.05.2023; Dove; Dove Medical Press
• Subjects: 16s rrna; Analysis; Bacteremia; Blood; Case Report; Diarrhea; Food allergy; Immunoglobulin E; Ionization; kalamiella piersonii; Mass spectrometry; matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; Medical examination; non-ige mediated gastrointestinal food allergy; RNA; Japan; 16S rRNA; Kalamiella piersonii; non-IgE-mediated gastrointestinal food allergy; matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
• ISSN: 1178-6973; 1178-6973
• DOI: 10.2147/IDR.S402364

is rare pathogen, and its pathogenicity to humans has been unknown. We describe an infant with bacteremia caused by . The patient was a 2-month-old girl presented with diarrhea, poor oral intake, and vomiting. The patient was tentatively diagnosed with acute enterocolitis. After admission, the patient developed a fever and blood culture yielded Gram-negative cocci, first determined to be by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. However, genetic analysis of 16S rRNA allowed its identification as (GenBank accession number is OQ547240). Other housekeeping genes such as , and also identified the isolated strain as . The patient was successfully treated with cefotaxime without sequelae. Later, the patient was diagnosed as non-IgE-mediated gastrointestinal food allergy. Our experience indicated that is a potential human pathogen that can cause invasive infections even in infants and children. Identification of is difficult with routine conventional tests, and detailed studies including genetic analyses are necessary to clarify the pathogenicity of in humans.