Improving survival for childhood cancer in Slovakia

• Published in: International journal of cancer Vol. 65; no. 5; pp. 594 - 600
• Main Authors: Kramárová, Eva, Plesko, Ivan, Black, Roger J., Obsitníková, Adriana
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01.03.1996; Wiley-Liss
• Subjects: Adolescent; Biological and medical sciences; Child; Child, Preschool; Female; General aspects; Humans; Infant; Male; Medical sciences; Neoplasms - diagnosis; Neoplasms - epidemiology; Neoplasms - therapy; Prognosis; Proportional Hazards Models; Registries; Slovakia; Survival Analysis; Tumors; Slovakia; Human; Evolution; Malignant tumor; Child; Statistical study; Survival
• ISSN: 0020-7136; 1097-0215
• DOI: 10.1002/(SICI)1097-0215(19960301)65:5<594::AID-IJC7>3.0.CO;2-Y

Data from the National Cancer Registry of Slovakia were used to evaluate survival for 2,958 childhood cancer patients registered between 1968 and 1987 and aged 0–14 years at diagnosis. Actuarial survival rates were computed for children diagnosed in 4 successive 5‐year periods and compared. Overall 5‐year survival rose from 20% for the period 1968–1972 to 46% for the period 1983–1987. The increase was statistically significant in age groups 1–4, 5–9 and 10–14 years. Survival for children aged less than 1 year also increased slightly, but this was not statistically significant. In most of the major diagnostic groups, survival increased markedly. Five‐year survival rose significantly for leukaemias, lymphomas, CNS neoplasms, Wilms' tumours, bone tumours, soft‐tissue sarcomas and germ‐cell tumours. Despite this progress, survival in Slovakia remains lower than the corresponding figures from registries in Western Europe and the United States. © 1996 Wiley‐Liss, Inc.