C4 article: Implications of COVID‐19 in transplantation

• Published in: American Journal of Transplantation Vol. 21; no. 5; pp. 1801 - 1815
• Main Author: Kumar, Deepali
• Format: Journal Article Web Resource
• Language: English
• Published: United States John Wiley & Sons, Inc 01.05.2021; Elsevier Limited; John Wiley and Sons Inc
• Subjects: Antiviral drugs; Blood & organ donations; Child; clinical research/practice; Coronaviridae; Coronaviruses; COVID-19; COVID-19 - diagnosis; COVID-19 diagnostic tests; COVID-19 Nucleic Acid Testing; Dexamethasone; Dexamethasone - therapeutic use; Humans; infection and infectious agents; infection and infectious agents – viral; infectious disease; Organ Transplantation; organ transplantation in general; Original; ORIGINAL ARTICLES; Patients; Pediatrics; Severe acute respiratory syndrome coronavirus 2; Tissue and Organ Procurement; Tissue Donors; Transplantation; Transplants & implants; infection and infectious agents; infectious disease; organ transplantation in general; infection and infectious agents - viral; clinical research/practice
• ISSN: 1600-6135; 1600-6143; 1600-6143
• DOI: 10.1111/ajt.16346

A novel coronavirus has had global impact on individual health and health care delivery. In this C4 article, contributors discuss various aspects of transplantation including donor and recipient screening, management of infected patients, and prevention of coronavirus disease (COVID). Donor screening with SARS‐CoV‐2 nucleic acid testing (NAT) close to the time of procurement is recommended. Many programs are also screening all potential recipients at the time of admission. The management of COVID has evolved with remdesivir emerging as a new potential option for transplant recipients. Dexamethasone has also shown promise and convalescent plasma is under study. Prevention strategies for transplant candidates and recipients are paramount. Pediatric‐specific issues are also discussed. Strategies for the psychological well‐being of patients and providers are also imperative, in addition to future research priorities for transplantation. This crowdsourced article summarizes the early state with regard to COVID‐19 and transplantation with state‐of‐the‐art commentaries on SARS‐CoV‐2 testing, treatment, prevention, transplant program management and the well‐being of the transplant team, including areas for future research.