Azadirachtin Story

Azadirachtin has been the subject of intensive research within the scientific community ever since its isolation from the neem tree in 1968. There are now over 1000 publications relating to this natural product which cover all aspects of structural, biological and synthetic studies. Herein, we descr...

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Bibliographic Details
Published inAngewandte Chemie (International ed.) Vol. 47; no. 49; pp. 9402 - 9429
Main Authors Veitch, Gemma E, Boyer, Alistair, Ley, Steven V
Format Journal Article
LanguageEnglish
Published Weinheim Wiley-VCH Verlag 24.11.2008
WILEY-VCH Verlag
WILEY‐VCH Verlag
Subjects
antifeedants
Azadirachta - chemistry
Claisen rearrangement
epoxidation
Limonins - chemical synthesis
Limonins - chemistry
Limonins - isolation & purification
natural products
radical cyclization
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Summary:Azadirachtin has been the subject of intensive research within the scientific community ever since its isolation from the neem tree in 1968. There are now over 1000 publications relating to this natural product which cover all aspects of structural, biological and synthetic studies. Herein, we describe the worldwide synthesis efforts towards this fascinating molecule.
Bibliography:http://dx.doi.org/10.1002/anie.200802675
Pfizer Global R+D
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Merck
ArticleID:ANIE200802675
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200802675