Chemical Design of Nanoparticle Probes for High-Performance Magnetic Resonance Imaging

Synthetic magnetic nanoparticles (MNPs) are emerging as versatile probes in biomedical applications, especially in the area of magnetic resonance imaging (MRI). Their size, which is comparable to biological functional units, and their unique magnetic properties allow their utilization as molecular i...

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Published inAngewandte Chemie (International ed.) Vol. 47; no. 28; pp. 5122 - 5135
Main Authors Jun, Young-wook, Lee, Jae-Hyun, Cheon, Jinwoo
Format Journal Article
LanguageEnglish
Published Weinheim Wiley-VCH Verlag 27.06.2008
WILEY-VCH Verlag
WILEY‐VCH Verlag
Subjects
Animals
Humans
magnetic properties
magnetic resonance imaging
Magnetic Resonance Imaging - methods
Magnetic Resonance Imaging - standards
medicinal chemistry
Molecular Probe Techniques
nanoparticles
Nanoparticles - chemistry
nanotechnology
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Summary:Synthetic magnetic nanoparticles (MNPs) are emerging as versatile probes in biomedical applications, especially in the area of magnetic resonance imaging (MRI). Their size, which is comparable to biological functional units, and their unique magnetic properties allow their utilization as molecular imaging probes. Herein, we present an overview of recent breakthroughs in the development of new synthetic MNP probes with which the sensitive and target-specific observation of biological events at the molecular and cellular levels is possible.
Bibliography:http://dx.doi.org/10.1002/anie.200701674
ArticleID:ANIE200701674
ark:/67375/WNG-S03VX3P2-B
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SourceType-Scholarly Journals-1
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content type line 23
ObjectType-Review-1
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200701674