Multifunctional Magneto-Polymeric Nanohybrids for Targeted Detection and Synergistic Therapeutic Effects on Breast Cancer

• Published in: Angewandte Chemie (International ed.) Vol. 46; no. 46; pp. 8836 - 8839
• Main Authors: Yang, Jaemoon, Lee, Choong-Hwan, Ko, Hyun-Ju, Suh, Jin-Suck, Yoon, Ho-Geun, Lee, Kwangyeol, Huh, Yong-Min, Haam, Seungjoo
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley-VCH Verlag 01.01.2007; WILEY-VCH Verlag; WILEY‐VCH Verlag
• Subjects: Animals; Antineoplastic Agents - therapeutic use; Breast Neoplasms - drug therapy; Cell Line, Tumor; drug delivery; Drug Delivery Systems; Female; Humans; hybrid composites; imaging agents; magnetic resonance; Magnetic Resonance Imaging; Magnetics; Mice; Nanomedicine - methods; Nanoparticles - therapeutic use; Neoplasms, Experimental - drug therapy; Polymers - therapeutic use; transmission electron microscopy

Diagnosis and treatment all in one: Multifunctional magneto‐polymeric nanohybrids (MMPNs) have been synthesized using ultrasensitive MnFe2O4 nanocrystals, chemotherapeutic agents, and encapsulating amphiphilic block copolymers for targeted detection by MRI and treatment of breast cancer. See the TEM...