Disinfection with sodium hypochlorite in hospital environmental surfaces in the reduction of contamination and infection prevention: a systematic review

• Published in: Revista da Escola de Enfermagem da U S P Vol. 49; no. 4; pp. 681 - 688
• Main Authors: Pereira, Samantha Storer Pesani, Oliveira, Hadelândia Milon de, Turrini, Ruth Natalia Teresa, Lacerda, Rúbia Aparecida
• Format: Journal Article
• Language: Portuguese; English
• Published: Brazil Universidade de São Paulo, Escola de Enfermagem 01.08.2015; SciELO
• Subjects: Cross Infection - prevention & control; Desinfección; Disinfectants; Disinfection; Equipment Contamination - prevention & control; Hipoclorito de Sodio; Hospitals; Humans; Infección Hospitalaria; Instituciones de Salud; NURSING; Revisión; Sodium Hypochlorite; Cross Infection; Disinfection; Instituciones de Salud; Review; Desinfecção; Infecção Hospitalar; Instituições de Saúde; Revisão; Health Facilities; Infección Hospitalaria; Revisión; Hipoclorito de Sodio; Hipoclorito de Sódio; Sodium Hypochlorite; Desinfección
• ISSN: 0080-6234; 1980-220X; 0080-6234; 1980-220X
• DOI: 10.1590/S0080-623420150000400020

To search for evidence of the efficiency of sodium hypochlorite on environmental surfaces in reducing contamination and prevention of healthcare-associated infection HAIs. Systematic review in accordance with the Cochrane Collaboration. We analyzed 14 studies, all controlled trials, published between 1989-2013. Most studies resulted in inhibition of microorganism growth. Some decreased infection, microorganism resistance and colonization, loss of efficiency in the presence of dirty and surface-dried viruses. The hypochlorite is an effective disinfectant, however, the issue of the direct relation with the reduction of HAIs remains. The absence of control for confounding variables in the analyzed studies made the meta-analysis performance inadequate. The evaluation of internal validity using CONSORT and TREND was not possible because its contents were not appropriate to laboratory and microbiological studies. As a result, there is an urgent need for developing specific protocol for evaluating such studies.