Development and Validation of an Eight-Item Brief Form of the SOAPP-R (SOAPP-8)

• Published in: Pain medicine (Malden, Mass.) Vol. 19; no. 10; pp. 1982 - 1987
• Main Authors: Black, Ryan A, McCaffrey, Stacey A, Villapiano, Albert J, Jamison, Robert N, Butler, Stephen F
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.10.2018
• Subjects: Addictive behaviors; Adult; Aged; Aged, 80 and over; Analgesics, Opioid - therapeutic use; Area Under Curve; Chronic pain; Chronic Pain - drug therapy; Drug abuse; Drug therapy; Female; Health behavior; Humans; Male; Mass Screening; Mental health surveys; Middle Aged; Narcotics; Opioid-Related Disorders - epidemiology; Opioids; Pain; Pain Clinics; Pain management; Quantitative psychology; Questionnaires; Reproducibility of Results; Retrospective Studies; Risk Assessment; ROC Curve; Validity; Young Adult; United States; United States > US; Screening; Aberrant Drug Behavior; Short Form; SOAPP-R; Opioids
• ISSN: 1526-2375; 1526-4637
• DOI: 10.1093/pm/pnx194

Abstract Objective Although the Screener and Opioid Assessment for Patients with Pain–Revised (SOAPP-R) has become a widely used screener for aberrant opioid-related behavior in adults, the length of the instrument may limit its utility. The purpose of the current study was to develop a short form of the SOAPP-R by retaining as few items as possible while maximizing predictive accuracy. Methods Participants (N = 555), recruited from pain clinics, completed the 24-item SOAPP-R and participated in a five-month follow-up visit to evaluate aberrant drug-related behaviors. Opioid aberrant-related behavior was determined through self-report, physician report, and urine toxicology screen. The optimal subset of SOAPP-R items to predict aberrant opioid-related behavior was identified empirically by employing the LASSO selection method and the leave-one-out cross-validation (LOOCV) method offered in the GLMSELECT procedure in SAS 9.4 in conjunction with content expertise. Results Eight items were identified before the selection method stopped. The receiver operating characteristic curve generated from the predicted probabilities from the model produced an area under the curve (AUC) value greater than the AUC value produced by the 24-item SOAPP-R total score and yielded a sensitivity of 0.74 and a specificity of 0.66. Conclusions These results provide strong preliminary support for the SOAPP-8 as a brief screening tool of aberrant opioid-related behavior in chronic pain patients.