Microbial differences between active and remission peri-implantitis

• Published in: Scientific reports Vol. 12; no. 1; p. 5284
• Main Authors: Hashimoto, Yuhei, Okada, Shinsuke, Yasuda, Keisuke, Kawagoe, Maiko, Kajiya, Mikihito, Tsuga, Kazuhiro
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 28.03.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 692/699; 692/699/3020; 692/699/3020/3028; Bacteria; Dental prosthetics; Etiology; Fusobacterium - genetics; Humanities and Social Sciences; Humans; Lactic acid; Lactic acid bacteria; Microbiomes; Microbiota - genetics; multidisciplinary; Peri-Implantitis - etiology; Peri-Implantitis - therapy; Remission; RNA, Ribosomal, 16S - genetics; rRNA 16S; Science; Science (multidisciplinary); Transplants & implants; Treponema - genetics
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-09192-y

Peri-implantitis has a polymicrobial etiology and is a major cause of dental implant loss. Various clinical protocols for its prevention and treatment have been proposed; however, some cases show a rapid progression with non-resolving clinical symptoms. To clear a means of differentiating between such cases, the implants with peri-implantitis in this study were categorized as the active group and the remission group and that two kinds of samples were obtained from the same subjects (n = 20). The microbiome was analyzed through pyrosequencing of the 16S rRNA gene. From LEfSe results, Porphyomonas , Fusobacterium , Treponema , Tannerella, and other periodontal pathogens were abundant in the active group, while lactic acid bacteria ( Lactobacillales and Bifidobacterium ) were abundant in the remission group.