Clinical and radiographic outcomes of total hip replacement with poly(2-methacryloyloxyethyl phosphorylcholine)-grafted highly cross-linked polyethylene liners: Three-year results of a prospective consecutive series

• Published in: Modern rheumatology Vol. 25; no. 2; pp. 286 - 291
• Main Authors: Takatori, Yoshio, Moro, Toru, Ishihara, Kazuhiko, Kamogawa, Morihide, Oda, Hiromi, Umeyama, Takashige, Kim, Yoon Taek, Ito, Hideya, Kyomoto, Masayuki, Tanaka, Takeyuki, Kawaguchi, Hiroshi, Tanaka, Sakae
• Format: Journal Article
• Language: English
• Published: United States Informa Healthcare 01.03.2015; Taylor & Francis
• Subjects: Adult; Aged; Arthroplasty; Arthroplasty, Replacement, Hip; Chromium; Cobalt; Female; Femur Head Necrosis - diagnostic imaging; Femur Head Necrosis - surgery; Hip Joint - diagnostic imaging; Hip Joint - surgery; Hip Prosthesis; Humans; Joint replacement; Joint replacement surgery; Male; Middle Aged; Molybdenum; Osteoarthritis, Hip - diagnostic imaging; Osteoarthritis, Hip - surgery; Phosphorylcholine - analogs & derivatives; Polyethylene; Polyethylene (UHMWPE); Polymethacrylic Acids; Prospective Studies; Radiography; Treatment Outcome; Wear; Wear resistance; Hip prosthesis; Arthroplasty; Joint replacement; Polyethylene (UHMWPE); Wear
• ISSN: 1439-7595; 1439-7609
• DOI: 10.3109/14397595.2014.941438

Abstract Objectives. This study aimed to evaluate the clinical safety and wear-resistance of the novel highly cross-linked polyethylene (HXLPE) acetabular liner with surface grafting of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) at 3 years after total hip replacement (THR). Methods. Eighty consecutive patients underwent cementless THR using a 26-mm diameter cobalt-chromium-molybdenum alloy femoral head and a PMPC-grafted HXLPE liner for the bearing couplings. We evaluated the clinical and radiographic outcomes of 76 patients at 3 years after the index surgery. Results. The clinical results at 3 years were equivalent to a Harris hip score of 95.6 points. No adverse events were associated with the implanted PMPC-grafted HXLPE liner, and no periprosthetic osteolysis was detected. The mean femoral head penetration rate was 0.002 mm/year, representing marked reduction compared with other HXLPE liners. Conclusions. A PMPC-grafted HXLPE liner is a safe option in THR and probably reduces the generation of wear particles.