An Overview of Recent Developments in the Management of Burn Injuries

• Published in: International journal of molecular sciences Vol. 24; no. 22; p. 16357
• Main Authors: Radzikowska-Büchner, Elżbieta, Łopuszyńska, Inga, Flieger, Wojciech, Tobiasz, Michał, Maciejewski, Ryszard, Flieger, Jolanta
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.11.2023
• Subjects: burn care; burn injuries; Burn treatment; Care and treatment; Debridement; dressing; Extracellular matrix; Hospitalization; Injuries; Mortality; Nutrition; Pain; Pain management; Patients; Plastic surgery; Post traumatic stress disorder; regenerative medicine; Scars; Skin; Skin & tissue grafts; skin grafts; skin tissue engineering; Sunburn & sun tanning; Tissue engineering; Wound healing; Poland; United Kingdom; Germany
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms242216357

According to the World Health Organization (WHO), around 11 million people suffer from burns every year, and 180,000 die from them. A burn is a condition in which heat, chemical substances, an electrical current or other factors cause tissue damage. Burns mainly affect the skin, but can also affect deeper tissues such as bones or muscles. When burned, the skin loses its main functions, such as protection from the external environment, pathogens, evaporation and heat loss. Depending on the stage of the burn, the patient’s condition and the cause of the burn, we need to choose the most appropriate treatment. Personalization and multidisciplinary collaboration are key to the successful management of burn patients. In this comprehensive review, we have collected and discussed the available treatment options, focusing on recent advances in topical treatments, wound cleansing, dressings, skin grafting, nutrition, pain and scar tissue management.