Fatal Neurological Disease in Scrapie-Infected Mice Induced for Experimental Autoimmune Encephalomyelitis

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Published inJournal of Virology Vol. 81; no. 18; pp. 9942 - 9949
Main Authors Friedman-Levi, Yael, Ovadia, Haim, Hoftberger, Romana, Einstein, Ofira, Abramsky, Oded, Budka, Herbert, Gabizon, Ruth
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.09.2007
Subjects
Animals
Astrocytes - immunology
Astrocytes - pathology
Biological and medical sciences
Biomarkers
Encephalomyelitis, Autoimmune, Experimental - complications
Encephalomyelitis, Autoimmune, Experimental - immunology
Encephalomyelitis, Autoimmune, Experimental - pathology
Female
Fundamental and applied biological sciences. Psychology
Humans
Inflammation - chemically induced
Inflammation - complications
Inflammation - immunology
Inflammation - pathology
Medulla Oblongata - immunology
Medulla Oblongata - pathology
Mice
Microbiology
Miscellaneous
Pathogenesis and Immunity
PrPSc Proteins - immunology
PrPSc Proteins - toxicity
Scrapie - chemically induced
Scrapie - complications
Scrapie - immunology
Scrapie - pathology
Spinal Cord - immunology
Spinal Cord - pathology
Spleen - immunology
Spleen - pathology
Time Factors
Virology
Prion disease
Nervous system diseases
Encephalomyelitis
Scrapie
Rodentia
Cerebral disorder
Virology
Infection
Vertebrata
Mammalia
Mouse
Animal
Central nervous system disease
Death
Sheep
Degenerative disease
Prion
Artiodactyla
Spongiform encephalopathy
Veterinary
Spinal cord disease
Ungulata
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Corresponding author. Mailing address: Department of Neurology, Hadassah University Hospital, Jerusalem, Israel. Phone: 972-2-6777858. Fax: 972-2-6429441. E-mail: gabizonr@hadassah.org.il
Y.F.-L., H.O., and R.H. contributed equally to this work.
ISSN:0022-538X
1098-5514
DOI:10.1128/JVI.00780-07