Bone healing after biodegradable mini-plate fixation

• Published in: Acta cirurgica brasileira Vol. 31; no. 6; pp. 364 - 370
• Main Authors: Atali, Onur, Gocmen, Gokhan, Aktop, Sertac, Ak, Esin, Basa, Selcuk, Cetinel, Sule
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 01.06.2016
• Subjects: Absorbable Implants; Absorbable Implants. Tomography; Animals; Bone and Bones - pathology; Bone and Bones - ultrastructure; Bone Remodeling - physiology; Electron Scanning. Rabbits; Female; Internal Fixators; Mandibular Osteotomy - instrumentation; Mandibular Osteotomy - rehabilitation; Microscopy, Electron, Scanning - methods; Models, Animal; Osteogenesis - physiology; Postoperative Period; Rabbits; Tomography, X-Ray Computed - methods; Wound Healing - physiology; X-Ray Computed. Mandibular Fractures. Osteotomy. Microscopy
• ISSN: 0102-8650; 1678-2674; 0102-8650
• DOI: 10.1590/S0102-865020160060000001

To compare bone healing in mandibular vertical body osteotomies (MVBO) after fixation with a resorbable 2.0mm-profile fixation system in the first and third postoperative months in rabbits. Twenty hemimandibles of ten rabbits were divided into two groups according to duration of resorbable fixation-one or three months. The MVBOs were performed and one four-hole, resorbable, 2.0mm mini-plate fixation system was used on each side. The computed tomography (CT) scans, scanning electron microscopy (SEM), and histomorphometric outcomes of groups I and II were compared. Significant differences were found between the one- and three- month assessments in terms of newly formed bone ratio values (p<0.05). There was more new bone formation at the third month on both the CT and histomorphometric examinations. A better adaptation of the bone tissues to the resorbable mini-plate and screws was observed on SEM at three months. The resorbable mini-plates provided a fixation stable enough to allow immediate oral alimentation and callus formation in both groups.