Vitamin E serum levels in Rett syndrome

In order to study the role of vitamin E in the pathogenesis of Rett syndrome (RS), we analysed vitamin E serum levels in twenty-eight patients affected by this disorder. We found lower vitamin E serum levels in nine cases (32.1%). These results indicated that the oxidative free radical metabolism ma...

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Published inJournal of the neurological sciences Vol. 156; no. 2; pp. 227 - 230
Main Authors Formichi, Patrizia, Battisti, Carla, Dotti, Maria Teresa, Hayek, Giuseppe, Zappella, Michele, Federico, Antonio
Format Journal Article
LanguageEnglish
Published Shannon Elsevier B.V 01.04.1998
Elsevier Science
Subjects
Adolescent
Adult
Biological and medical sciences
Child
Child, Preschool
Cholesterol - blood
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Female
Humans
Medical sciences
Neurology
Rett syndrome
Rett Syndrome - blood
Vitamin E
Vitamin E - blood
Vitamin E
Rett syndrome
Human
Nervous system diseases
Pathogenesis
Central nervous system disease
Exploration
Serum
α-Tocopherol
Degenerative disease
Child
Cerebral disorder
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Summary:In order to study the role of vitamin E in the pathogenesis of Rett syndrome (RS), we analysed vitamin E serum levels in twenty-eight patients affected by this disorder. We found lower vitamin E serum levels in nine cases (32.1%). These results indicated that the oxidative free radical metabolism may be impaired in a significant percentage of Rett syndrome patients suggesting the need for further studies of tissue vitamin E in different brain regions.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0022-510X
1878-5883
DOI:10.1016/S0022-510X(98)00035-5