Posterior reversible encephalopathy syndrome

The posterior reversible encephalopathy syndrome (PRES) is a neurological disorder of (sub)acute onset characterized by varied neurological symptoms, which may include headache, impaired visual acuity or visual field deficits, disorders of consciousness, confusion, seizures, and focal neurological d...

Full description

Saved in:
Bibliographic Details
Published inJournal of neurology Vol. 264; no. 8; pp. 1608 - 1616
Main Authors Fischer, Marlene, Schmutzhard, Erich
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2017
Springer Nature B.V
Subjects
Acuity
Autoimmune diseases
Blood pressure
Consciousness
Cytotoxicity
Edema
Encephalopathy
Epilepsy
Headache
Humans
Kidney transplantation
Magnetic resonance imaging
Medicine
Medicine & Public Health
Neuroimaging
Neurological complications
Neurological diseases
Neurology
Neuroradiology
Neurosciences
Posterior Leukoencephalopathy Syndrome - diagnosis
Posterior Leukoencephalopathy Syndrome - etiology
Posterior Leukoencephalopathy Syndrome - physiopathology
Posterior Leukoencephalopathy Syndrome - therapy
Preeclampsia
Review
Seizures
Sepsis
Visual field
Vasogenic edema
Chemotherapy
Encephalopathy
Preeclampsia
Hypertensive encephalopathy
Online AccessGet full text

Cover

More Information
Summary:The posterior reversible encephalopathy syndrome (PRES) is a neurological disorder of (sub)acute onset characterized by varied neurological symptoms, which may include headache, impaired visual acuity or visual field deficits, disorders of consciousness, confusion, seizures, and focal neurological deficits. In a majority of patients the clinical presentation includes elevated arterial blood pressure up to hypertensive emergencies. Neuroimaging, in particular magnetic resonance imaging, frequently shows a distinctive parieto-occipital pattern with a symmetric distribution of changes reflecting vasogenic edema. PRES frequently develops in the context of cytotoxic medication, (pre)eclampsia, sepsis, renal disease or autoimmune disorders. The treatment is symptomatic and is determined by the underlying condition. The overall prognosis is favorable, since clinical symptoms as well as imaging lesions are reversible in most patients. However, neurological sequelae including long-term epilepsy may persist in individual cases.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0340-5354
1432-1459
DOI:10.1007/s00415-016-8377-8