A Review of Commercial Developments and Recent Laboratory Research of Dialyzers and Membranes for Hemodialysis Application

Dialyzers have been commercially used for hemodialysis application since the 1950s, but progress in improving their efficiencies has never stopped over the decades. This article aims to provide an up-to-date review on the commercial developments and recent laboratory research of dialyzers for hemodi...

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Published inMembranes (Basel) Vol. 11; no. 10; p. 767
Main Authors Said, Noresah, Lau, Woei Jye, Ho, Yeek-Chia, Lim, Soo Kun, Zainol Abidin, Muhammad Nidzhom, Ismail, Ahmad Fauzi
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 07.10.2021
MDPI
Subjects
Abdomen
Biocompatibility
blood
commercial dialyzer
Dialysate
dialysis
dialyzer design
Dialyzers
Epidemiology
Flow distribution
Flow simulation
Health care
Hemodialysis
Hollow fiber membranes
Kidney diseases
Laboratories
membrane
Membranes
Patients
Peritoneal dialysis
Permeability
Review
Sterilization
Transplants & implants
Urea
United Kingdom > UK
Asia
United States > US
Europe
China
Japan
North America
Germany
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Summary:Dialyzers have been commercially used for hemodialysis application since the 1950s, but progress in improving their efficiencies has never stopped over the decades. This article aims to provide an up-to-date review on the commercial developments and recent laboratory research of dialyzers for hemodialysis application and to discuss the technical aspects of dialyzer development, including hollow fiber membrane materials, dialyzer design, sterilization processes and flow simulation. The technical challenges of dialyzers are also highlighted in this review, which discusses the research areas that need to be prioritized to further improve the properties of dialyzers, such as flux, biocompatibility, flow distribution and urea clearance rate. We hope this review article can provide insights to researchers in developing/designing an ideal dialyzer that can bring the best hemodialysis treatment outcomes to kidney disease patients.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2077-0375
2077-0375
DOI:10.3390/membranes11100767