Synthesis of hydroxyapatite nanoparticles in ultrasonic precipitation

• Published in: Ceramics international Vol. 31; no. 8; pp. 1041 - 1044
• Main Authors: Cao, Li-yun, Zhang, Chuan-bo, Huang, Jian-feng
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 2005; Elsevier Science
• Subjects: A. Powders: chemical preparation; Applied sciences; Biological and medical sciences; Building materials. Ceramics. Glasses; Ceramic industries; Chemical industry and chemicals; Cross-disciplinary physics: materials science; rheology; D. Apatite; Exact sciences and technology; Kinetics; Materials science; Medical sciences; Miscellaneous; Nanocrystalline materials; Nanoscale materials and structures: fabrication and characterization; Physics; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Technical ceramics; Technology. Biomaterials. Equipments. Material. Instrumentation; A. Powders: chemical preparation; D. Apatite; Kinetics; Scanning electron microscopy; Chemical precipitation; Nanoparticle; Crystallization; Hydroxyapatite; Experimental study; X ray diffraction; Oxide ceramics; Calcium Hydroxides phosphates; Morphology; Technical ceramics; Ceramic biomaterial; Manufacturing; Nanocrystal; Ultrasonic method
• ISSN: 0272-8842; 1873-3956
• DOI: 10.1016/j.ceramint.2004.11.002

Nanocrystalline hydroxyapatite (HAp) was prepared by a precipitation method with aid of ultrasonic irradiation using Ca(NO 3) 2 and NH 4H 2PO 4 as source material and carbamide (NH 2CONH 2) as precipitator. The crystallization and morphology of the prepared nanoparticles were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The mechanism and kinetics of the nano-hydroxyapatite were considered in particular, and the influence of the temperature and time on the HAp formation rate was also investigated. The results show that the needle-like HAp crystalline was prepared by the ultrasonic precipitation process. The HAp content increases with the preparation temperature and time. The adding of carbamide is helpful for formation of HAp nanoparticles. An Arrhenius relationship was found between the HAp formation rate and the temperature, and an apparent activation energy of 59.9 kJ/mol was obtained by calculation.