STAT5 and CD4 + T Cell Immunity [version 1; peer review: 4 approved]

STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4 + helper and regulatory T-cell subsets.

Saved in:
Bibliographic Details
Published inF1000 research Vol. 6; p. 32
Main Authors Owen, David L, Farrar, Michael A
Format Journal Article
LanguageEnglish
Published England Faculty of 1000 Ltd 2017
F1000Research
F1000 Research Ltd
Subjects
Autoimmunity
Innate Immunity
Leukocyte Development
Leukocyte Signaling & Gene Expression
Lymphocytes T
Review
T-cell development
T-cell function
STAT5
Online AccessGet full text

Cover

More Information
Summary:STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4 + helper and regulatory T-cell subsets.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Competing interests: The authors declare that they have no competing interests.
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.9838.1