Predicting Dimensions in Microfluidic Paper Based Analytical Devices

The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable mi...

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Bibliographic Details
Published inSensors (Basel, Switzerland) Vol. 21; no. 1; p. 101
Main Authors Catalan-Carrio, Raquel, Akyazi, Tugçe, Basabe-Desmonts, Lourdes, Benito-Lopez, Fernando
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 26.12.2020
MDPI
Subjects
Design
Fluid dynamics
Fluid flow
Heating
Laser etching
LOC
Mass production
Methods
Microfluidics
paper microfluidics
paper microfluidics fabrication
Software
wax printing
Waxes
µPAD
LOC
paper microfluidics
µPAD
wax printing
paper microfluidics fabrication
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Summary:The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable microfluidic channels. The most common paper microfluidic fabrication method is wax printing, which consists of two parts, printing and heating, where heating is a critical step for the fabrication of reproducible device dimensions. In order to bring paper-based devices to success, it is essential to optimize the fabrication process in order to always get a reproducible device. Therefore, the optimization of the heating process and the analysis of the parameters that could affect the final dimensions of the device, such as its shape, the width of the wax barrier and the internal area of the device, were performed. Moreover, we present a method to predict reproducible devices with controlled working areas in a simple manner.
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Both authors contributed equally to this work.
ISSN:1424-8220
1424-8220
DOI:10.3390/s21010101