LOCAL ANESTHETICS AND STEROIDS: CONTRAINDICATIONS AND COMPLICATIONS - CLINICAL UPDATE

• Published in: Acta clinica Croatica (Tisak) Vol. 58; no. Suppl 1; pp. 53 - 61
• Main Authors: Šimurina, Tatjana, Mraović, Boris, Župčić, Miroslav, Graf Župčić, Sandra, Vulin, Marina
• Format: Journal Article
• Language: English
• Published: Croatia Klinicki bolnicki centar Sestre milosrdnice 01.07.2019; Sestre Milosrdnice University Hospital and Institute of Clinical Medical Research, Vinogradska cesta c. 29 Zagreb
• Subjects: Acute Pain - drug therapy; Adrenal Cortex Hormones - adverse effects; Analgesia; Analgesics; Anesthesia; Anesthesia, Conduction - adverse effects; Anesthesia, Local - adverse effects; Anesthetics, Local - adverse effects; Benzocaine; Bupivacaine; Chronic pain; Chronic Pain - drug therapy; Complications and side effects; Contraindications, Drug; Humans; Methylene blue; Pain management; Pain Management - adverse effects; Pain Management - methods; Reviews; Croatia; Anesthetics, Local/adverse effects; Anesthetics, Local/complications; Steroids/adverse effects; Steroids/complications; Regional anesthesia and analgesia; Anesthetics, Local/toxicity; Anesthetics, Local
• ISSN: 0353-9466; 1333-9451
• DOI: 10.20471/acc.2019.58.s1.08

The objective of this clinical update, based on recently published literature, was to discuss incidence and characteristics of the most relevant clinical adverse effects associated with local anesthetic and steroid use in regional anesthesia and treatment of acute or chronic pain. A comprehensive review of the English-language medical literature search utilizing PubMed, Ovid Medline® and Google Scholar from 2015 to 2018 was performed. This narrative review provides anesthesia practitioners with updated evidences on complications and contraindications of local anesthetic and steroid use with emphasis on current points of view regarding prevention, early diagnosis and treatment of adverse events.