Inflammation in Complicated Pregnancy and Its Outcome

• Published in: American journal of perinatology Vol. 33; no. 14; p. 1337
• Main Authors: Kalagiri, Ram R, Carder, Timothy, Choudhury, Saiara, Vora, Niraj, Ballard, Amie R, Govande, Vinayak, Drever, Nathan, Beeram, Madhava R, Uddin, M Nasir
• Format: Journal Article
• Language: English
• Published: United States 01.12.2016
• Subjects: Chemokines - metabolism; Diabetes, Gestational - immunology; Female; Fetal Growth Retardation - immunology; Hormones - metabolism; Humans; Immunity, Cellular; Immunity, Innate; Infant, Newborn; Inflammation - physiopathology; Obesity - immunology; Pre-Eclampsia - immunology; Pregnancy; Pregnancy Complications - immunology; Pregnancy Outcome; Premature Birth - immunology; Toll-Like Receptors - metabolism

Normal pregnancy relies on a careful balance between immune tolerance and suppression. It is known that strict regulation of maternal immune function, in addition to components of inflammation, is paramount to successful pregnancy, and any imbalance between proinflammatory and anti-inflammatory cyto...