Clinicopathological characteristics and its association with digestive system tumors of 1111 patients with Schistosomiasis japonica
Schistosomiasis japonicum can cause different degrees of organ damage and complex human immune pathological reactions, which often invade the intestine and liver. The purpose of this study was to explore the pathological types and pathological changes of Schistosomiasis and their correlation with so...
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Published in | Scientific reports Vol. 13; no. 1; pp. 15115 - 11 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
13.09.2023
Nature Publishing Group Nature Portfolio |
Subjects | |
Online Access | Get full text |
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Summary: | Schistosomiasis japonicum
can cause different degrees of organ damage and complex human immune pathological reactions, which often invade the intestine and liver. The purpose of this study was to explore the pathological types and pathological changes of
Schistosomiasis
and their correlation with some digestive system tumors. Hematoxylin eosin staining was performed on the diseased tissues of 1111
Schistosomiasis
cases. We counted the deposition sites of
Schistosoma
eggs, analyzed the pathological characteristics, and compared the clinicopathological characteristics of
Schistosomiasis
associated digestive system tumors and non-
Schistosomiasis
digestive system tumors. We found that
Schistosoma japonicum
can cause multi organ and multi system damage, with 469 cases of inflammation, 47 cases of adenoma, and 519 cases of adenocarcinoma. Other types include cysts, stromal tumors, malignant lymphomas, and neuroendocrine tumors.
Schistosomiasis
associated tumors, including gastric cancer, liver cancer, colon cancer and rectal cancer, were compared with non-
Schistosomiasis
tumors. There were significant differences in age, gender and tumor differentiation between the two groups. Our study shows
Schistosomiasis
is a systemic disease, causing multiple organ and system damage in the human body. Its clinicopathological types are diverse, and there may be a pathological change process of “Inflammation-adenoma-carcinoma”.
Schistosomiasis
associated digestive system tumors differ from non-
Schistosomiasis
tumors in some clinicopathological features. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2045-2322 2045-2322 |
DOI: | 10.1038/s41598-023-42456-9 |