The microbiomic signature of hemorrhoids and comparison with associated microbiomes

Hemorrhoids are a common ailment that can cause significant disruptions to one’s daily life. While some researchers have speculated about a potential link between hemorrhoid development and gut microbes, there is currently insufficient evidence to support this claim. In this study, we collected samp...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in microbiology Vol. 15; p. 1329976
Main Authors Wang, Yuquan, Su, Wenya, Liu, Zhiqiang, Wang, Yihua, Li, Ling, Xu, Hai, Wang, Mingyu, Shen, Wenlong
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 13.05.2024
Subjects
bacterial infection
hemorrhoids
microbial community structure
Microbiology
microbiomic
thrombosed hemorrhoid
microbial community structure
thrombosed hemorrhoid
bacterial infection
microbiomic
hemorrhoids
Online AccessGet full text

Cover

More Information
Summary:Hemorrhoids are a common ailment that can cause significant disruptions to one’s daily life. While some researchers have speculated about a potential link between hemorrhoid development and gut microbes, there is currently insufficient evidence to support this claim. In this study, we collected samples from 60 hemorrhoid patients and analyzed the composition and characteristics of microbiomes in hemorrhoids. PCoA results revealed distinct differences between the microbiomes of hemorrhoids, skin-originated microbiomes, and gut microbes, highlighting the complex nature of hemorrhoidal microbiomes. The distribution characteristics of Staphylococcus suggest that the skin microbiome influences the microbiome of hemorrhoids. Additionally, we observed higher levels of Prevotella in two cases of thrombosed hemorrhoids compared to non-thrombosed hemorrhoids. This finding suggests that Prevotella may play a crucial role in the development of thrombosed hemorrhoids.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Edited by: Thi Thu Hao Van, RMIT University, Australia
These authors have contributed equally to this work
Reviewed by: Jinlyung Choi, PrognomiQ Inc., United States
Vincenzo Davide Palumbo, Euro-Mediterranean Institute of Science and Technology (IEMEST), Italy
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2024.1329976