Maternal trait anxiety, depression and life event stress in pregnancy: relationships with infant temperament

• Published in: Early human development Vol. 81; no. 2; pp. 183 - 190
• Main Authors: Austin, Marie-Paule, Hadzi-Pavlovic, Dusan, Leader, Leo, Saint, Karen, Parker, Gordon
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier Ireland Ltd 01.02.2005; New York,NY Elsevier; Amsterdam The Lancet Publishing Group, a division of Elsevier Science Ltd
• Subjects: Adult and adolescent clinical studies; Anxiety; Anxiety Disorders - psychology; Biological and medical sciences; Case studies; Depression; Depression - psychology; Depression, Mental; Female; Humans; Infant; Infant, Newborn; Infants; Maternal-fetal exchange; Medical sciences; Mood disorders; Mothers - psychology; Pregnancy; Pregnancy Trimester, Third; Prenatal; Prenatal care; Prospective Studies; Psychological aspects; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Regression Analysis; Risk factors; Stress; Stress, Psychological - psychology; Surveys and Questionnaires; Temperament; United States; Pregnancy; Prenatal; Infant; Anxiety; Temperament; Stress; Human; Affect affectivity; Mother; Female
• ISSN: 0378-3782; 1872-6232
• DOI: 10.1016/j.earlhumdev.2004.07.001

To assess whether links exist between maternal trait anxiety (STAI), perceived life event (LE) stress and depression (Edinburgh scale) and infant temperament. Women in the third trimester of pregnancy returned psychological self-report questionnaires; infant temperament was evaluated at 4 and 6 months by maternal and paternal report, while depression (concurrent Edinburgh scale) was also assessed at four and six months. As data were returned inconsistently at 4 and 6 months, we combined these two time points for simplicity of reporting and optimisation of numbers. Univariate logistic regressions on 970 subjects indicated that the pregnancy STAI (>40) scores were associated with 2.56- and 1.57-fold increases (maternal and paternal, respectively), in the odds of “difficult” infant temperament at 4 or 6 months. Concurrent Edinburgh scores (OR of 3.06 and 2.64 for maternal reports, respectively) were also predictive of infant temperament. Age, education, income, marital status, obstetric complications, infant gender and prematurity were not predictive of infant temperament. In stepwise multiple logistic regression analyses, the antenatal trait STAI (odds ratio 1.96) significantly predicted maternal reports of “difficult” temperament at 4 or 6 months independent of both antenatal and postnatal depression scores. There were similar trends for paternal reports of “difficult” temperament but these were not significant. Antenatal depression and perceived LE stress were not predictive of temperament. Finally, women ( N=14) reporting domestic violence (DV) in pregnancy had highly significant increased Edinburgh and STAI scores. Maternal trait anxiety was predictive of “difficult” infant temperament, independent of “concurrent” depression and key sociodemographic and obstetric risk factors. These findings, while needing replication using objective measures of infant temperament, suggest that antenatal psychological interventions aimed at minimising anxiety may optimize infant temperament outcomes. There may be some benefit in shaping specific interventions to women reporting specific risk factors such as DV or past abuse.