Effect of Shot Noise on Simultaneous Sensing in Frequency Division Multiplexed Diffuse Optical Tomographic Imaging Process

• Published in: Sensors (Basel, Switzerland) Vol. 17; no. 12; p. 2752
• Main Authors: Jang, Hansol, Lim, Gukbin, Hong, Keum-Shik, Cho, Jaedu, Gulsen, Gultekin, Kim, Chang-Seok
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28.11.2017; MDPI
• Subjects: Absorptivity; Breast cancer; Data acquisition; diffuse optical tomography; Frequency division multiplexing; Image acquisition; Medical imaging; Optical communication; Optical data processing; Oxygenation; Shot noise; Time division multiplexing; Tomography; shot noise; diffuse optical tomography; frequency-division multiplexing; time-division multiplexing
• ISSN: 1424-8220; 1424-8220
• DOI: 10.3390/s17122752

Diffuse optical tomography (DOT) has been studied for use in the detection of breast cancer, cerebral oxygenation, and cognitive brain signals. As optical imaging studies have increased significantly, acquiring imaging data in real time has become increasingly important. We have developed frequency-division multiplexing (FDM) DOT systems to analyze their performance with respect to acquisition time and imaging quality, in comparison with the conventional time-division multiplexing (TDM) DOT. A large tomographic area of a cylindrical phantom 60 mm in diameter could be successfully reconstructed using both TDM DOT and FDM DOT systems. In our experiment with 6 source-detector (S-D) pairs, the TDM DOT and FDM DOT systems required 6.18 and 1 s, respectively, to obtain a single tomographic data set. While the absorption coefficient of the reconstruction image was underestimated in the case of the FDM DOT, we experimentally confirmed that the abnormal region can be clearly distinguished from the background phantom using both methods.