Assessment of the anterior scleral thickness in central serous chorioretinopathy patients by optical coherence tomography

• Published in: Japanese journal of ophthalmology Vol. 65; no. 6; pp. 769 - 776
• Main Authors: Fernández-Vigo, José Ignacio, Moreno-Morillo, Francisco Javier, Shi, Hang, Ly-Yang, Fernando, Burgos-Blasco, Bárbara, Güemes-Villahoz, Noemí, Donate-López, Juan, García-Feijóo, Julián
• Format: Journal Article
• Language: English
• Published: Tokyo Springer Japan 01.11.2021; Springer Nature B.V
• Subjects: Clinical Investigation; Comparative studies; Medicine; Medicine & Public Health; Ophthalmology; Optical Coherence Tomography; Quadrants; Thickness; Tomography; Anterior scleral thickness; Optical coherence tomography; Central serous chorioretinopathy; Supraciliary space; Sclera
• ISSN: 0021-5155; 1613-2246
• DOI: 10.1007/s10384-021-00870-4

Purpose To assess the anterior scleral thickness (AST) and describe the presence of a visible supraciliary space (SCS) in central serous chorioretinopathy (CSC) patients by swept-source optical coherence tomography (SS-OCT). Study design Cross-sectional comparative study. Material and Methods Three groups were studied: 1) 64 eyes of 54 patients with CSC with persistent subretinal fluid (SRF); 2) 42 fellow eyes of CSC patients without SRF; 3) 65 eyes of 65 controls matched by age, sex and axial length (AL). The AST was measured in the temporal and nasal quadrants at 0, 1, and 2 mm from the scleral spur by SS-OCT. The presence of a visible SCS was also assessed. Results No differences were observed in the AST0 among the three groups (p≥ 0.665). The temporal AST1 was significantly thicker in the CSC group (530.3 ±67.1 µm) than in the controls (505.5 ±73.9; p=0.041). Mean AST2 was also thicker in the CSC group and the fellow eyes both for the temporal (519.4 ±89.1 µm and 519.8 ±98.5 µm respectively) and nasal quadrants (564.2 ±124.9 µm and 570.5 ±131.0 µm) than in the controls (450.1 ±76.8 and 473.3 ±111.6 µm) (all p≤0.001). A visible SCS was detected in the eyes of 8 CSC patients, in 4 fellow eyes and only in 1 control eye. Conclusions AST measured by SS-OCT was significantly greater in CSC eyes than in healthy eyes. Also, a visible SCS was detected in CSC eyes. Thus, thicker sclera in CSC eyes could be associated with the physiopathology of this disease.