Chronic low-grade inflammation and ovarian dysfunction in women with polycystic ovarian syndrome, endometriosis, and aging

• Published in: Frontiers in endocrinology (Lausanne) Vol. 14; p. 1324429
• Main Authors: Orisaka, Makoto, Mizutani, Tetsuya, Miyazaki, Yumiko, Shirafuji, Aya, Tamamura, Chiyo, Fujita, Masayuki, Tsuyoshi, Hideaki, Yoshida, Yoshio
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 13.12.2023
• Subjects: Aging; Endocrinology; Endometriosis; Female; Fibrosis; follicular microenvironment; Humans; inflammation; Inflammation - complications; ovarian dysfunction; polycystic ovarian syndrome; Polycystic Ovary Syndrome - complications; Tumor Microenvironment; endometriosis; aging; follicular microenvironment; inflammation; ovarian dysfunction; polycystic ovarian syndrome

The ovarian microenvironment is critical for follicular development and oocyte maturation. Maternal conditions, including polycystic ovary syndrome (PCOS), endometriosis, and aging, may compromise the ovarian microenvironment, follicular development, and oocyte quality. Chronic low-grade inflammatio...