Decreasing and stabilising trends of antimicrobial consumption and resistance in Escherichia coli and Klebsiella pneumoniae in segmented regression analysis, European Union/European Economic Area, 2001 to 2018

• Published in: Euro surveillance : bulletin européen sur les maladies transmissibles Vol. 24; no. 46; p. 1
• Main Authors: Peñalva, Germán, Högberg, Liselotte Diaz, Weist, Klaus, Vlahović-Palčevski, Vera, Heuer, Ole, Monnet, Dominique L
• Format: Journal Article
• Language: English
• Published: Sweden Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS) 14.11.2019; European Centre for Disease Prevention and Control (ECDC)
• Subjects: Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; Antimicrobial agents; Antimicrobial Stewardship - trends; Cephalosporins - administration & dosage; Cephalosporins - pharmacology; Cephalosporins - therapeutic use; Drug resistance; Drug Resistance, Multiple, Bacterial - drug effects; Drug Utilization - trends; E coli; Escherichia coli - drug effects; Escherichia coli - isolation & purification; Escherichia coli Infections - drug therapy; Escherichia coli Infections - microbiology; European Union; Fluoroquinolones - administration & dosage; Fluoroquinolones - pharmacology; Fluoroquinolones - therapeutic use; Health surveillance; Humans; Klebsiella Infections - drug therapy; Klebsiella Infections - microbiology; Klebsiella pneumoniae - drug effects; Klebsiella pneumoniae - isolation & purification; Microbial Sensitivity Tests; Population Surveillance; Public health; Rapid Communication; carbapenem; antimicrobial resistance; defined daily dose; fluoroquinolone; Escherichia coli; third-generation cephalosporin; bacterial infections; Antimicrobial consumption; Klebsiella pneumoniae
• ISSN: 1560-7917; 1025-496X; 1560-7917
• DOI: 10.2807/1560-7917.ES.2019.24.46.1900656

Investments to reduce the spread of antimicrobial resistance (AMR) in the European Union have been made, including efforts to strengthen prudent antimicrobial use. Using segmented regression, we report decreasing and stabilising trends in data reported to the European Surveillance of Antimicrobial Consumption Network and stabilising trends in data reported to the European Antimicrobial Resistance Surveillance Network. Our results could be an early indication of the effect of prioritising AMR on the public health agenda.