Akkermansia muciniphila : a potential candidate for ameliorating metabolic diseases

Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of and the occurrence of metabolic diseases. , a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivati...

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Published inFrontiers in immunology Vol. 15; p. 1370658
Main Authors Niu, Huifang, Zhou, Minfeng, Zogona, Daniel, Xing, Zheng, Wu, Ting, Chen, Rui, Cui, Dandan, Liang, Fengxia, Xu, Xiaoyun
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 20.03.2024
Subjects
Akkermansia
Akkermansia muciniphila
Diabetes Mellitus, Type 2
gut microbiota
health
Humans
Immunology
Intestines
metabolic diseases
Obesity
Verrucomicrobia - metabolism
health
Akkermansia muciniphila
metabolic diseases
gut microbiota
obesity
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Abstract Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of and the occurrence of metabolic diseases. , a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivatives have various physiological functions, including treating metabolic disorders and maintaining human health. This review systematically explicates the abundance change rules of in metabolic diseases. It also details the high efficacy and specific molecules mechanism of and its derivatives in treating obesity, type 2 diabetes mellitus, cardiovascular disease, and non-alcoholic fatty liver disease.
AbstractList Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of and the occurrence of metabolic diseases. , a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivatives have various physiological functions, including treating metabolic disorders and maintaining human health. This review systematically explicates the abundance change rules of in metabolic diseases. It also details the high efficacy and specific molecules mechanism of and its derivatives in treating obesity, type 2 diabetes mellitus, cardiovascular disease, and non-alcoholic fatty liver disease.
Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of Akkermansia muciniphila and the occurrence of metabolic diseases. A. muciniphila, a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivatives have various physiological functions, including treating metabolic disorders and maintaining human health. This review systematically explicates the abundance change rules of A. muciniphila in metabolic diseases. It also details the high efficacy and specific molecules mechanism of A. muciniphila and its derivatives in treating obesity, type 2 diabetes mellitus, cardiovascular disease, and non-alcoholic fatty liver disease.
Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of Akkermansia muciniphila and the occurrence of metabolic diseases. A. muciniphila , a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivatives have various physiological functions, including treating metabolic disorders and maintaining human health. This review systematically explicates the abundance change rules of A. muciniphila in metabolic diseases. It also details the high efficacy and specific molecules mechanism of A. muciniphila and its derivatives in treating obesity, type 2 diabetes mellitus, cardiovascular disease, and non-alcoholic fatty liver disease.
Author Xu, Xiaoyun
Niu, Huifang
Zogona, Daniel
Cui, Dandan
Zhou, Minfeng
Liang, Fengxia
Xing, Zheng
Chen, Rui
Wu, Ting
AuthorAffiliation 2 Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei , China
1 Key Laboratory of Environment Correlative Dietology (Ministry of Education), Hubei Key Laboratory of Fruit Vegetable Processing Quality Control (Huazhong Agricultural University), School of Food Science and Technology, Huazhong Agricultural University , Wuhan, Hubei , China
3 School of Acupuncture and Bone Injury, Hubei University of Chinese Medicine , Wuhan , China
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  givenname: Dandan
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Copyright Copyright © 2024 Niu, Zhou, Zogona, Xing, Wu, Chen, Cui, Liang and Xu.
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Keywords health
Akkermansia muciniphila
metabolic diseases
gut microbiota
obesity
Language English
License Copyright © 2024 Niu, Zhou, Zogona, Xing, Wu, Chen, Cui, Liang and Xu.
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Edited by: Subash Babu, International Centers for Excellence in Research (ICER), India
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SubjectTerms Akkermansia
Akkermansia muciniphila
Diabetes Mellitus, Type 2
gut microbiota
health
Humans
Immunology
Intestines
metabolic diseases
Obesity
Verrucomicrobia - metabolism
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Title Akkermansia muciniphila : a potential candidate for ameliorating metabolic diseases
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