Akkermansia muciniphila : a potential candidate for ameliorating metabolic diseases

Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of and the occurrence of metabolic diseases. , a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivati...

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Published inFrontiers in immunology Vol. 15; p. 1370658
Main Authors Niu, Huifang, Zhou, Minfeng, Zogona, Daniel, Xing, Zheng, Wu, Ting, Chen, Rui, Cui, Dandan, Liang, Fengxia, Xu, Xiaoyun
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 20.03.2024
Subjects
Akkermansia
Akkermansia muciniphila
Diabetes Mellitus, Type 2
gut microbiota
health
Humans
Immunology
Intestines
metabolic diseases
Obesity
Verrucomicrobia - metabolism
health
Akkermansia muciniphila
metabolic diseases
gut microbiota
obesity
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Summary:Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative studies have shown a certain correlation between the fluctuating abundance of and the occurrence of metabolic diseases. , a potential probiotic candidate colonized in the human intestinal mucus layer, and its derivatives have various physiological functions, including treating metabolic disorders and maintaining human health. This review systematically explicates the abundance change rules of in metabolic diseases. It also details the high efficacy and specific molecules mechanism of and its derivatives in treating obesity, type 2 diabetes mellitus, cardiovascular disease, and non-alcoholic fatty liver disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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Edited by: Subash Babu, International Centers for Excellence in Research (ICER), India
Suganthi Balasubramanian, International Centers for Excellence in Research (ICER), India
Reviewed by: Anuradha Rajamanickam, International Centers for Excellence in Research (ICER), India
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2024.1370658