Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite

• Published in: Sensors (Basel, Switzerland) Vol. 18; no. 4; p. 1223
• Main Authors: Queiroz, Daniely Ferreira de, Dadamos, Tony Rogério de Lima, Machado, Sergio Antonio Spinola, Martines, Marco Antonio Utrera
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 16.04.2018; MDPI
• Subjects: Carbon; Catalysis; Catecholamines; cobalt ferrite; Cobalt ferrites; Electrical measurement; Electrochemical analysis; electrode modified; Electrodes; Glassy carbon; Nanoparticles; Nanotubes; Noradrenaline; Norepinephrine; Oxidation; Silver; Silver chloride; Transmission electron microscopy; X-ray diffraction; cobalt ferrite; electrode modified; noradrenaline
• ISSN: 1424-8220; 1424-8220
• DOI: 10.3390/s18041223

This study describes the electrochemical preparation of the electrocatalytic oxidation/reduction of noradrenaline in modified glassy carbon of cobalt ferrite nanoparticles and carbon nanotubes (GC/MWCNT/FCo ). The cobalt ferrite powder was characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The optimum conditions found in an electrode composition were 4 μL of cobalt ferrite and 10 μL of carbon nanotubes in 0.1 mol L PBS at pH 7.0. The electrode displays electrochemical behavior in a wide potential range (-0.4 to 1.0 V vs. Ag/AgCl), high conductivity, and electrode stability/durability in 0.1 mol L PBS. Catalytic oxidation of noradrenaline was performed at the unmodified GC electrode at +0.60 V vs. Ag/AgCl and current of 0.17 μA and modified GC with cobalt ferrite nanoparticles and carbon nanotubes at +0.54 V vs. Ag/AgCl and current of 0.23 mA. With regard to the anodic peak current ( ) versus noradrenaline concentration by means of the amperometric method at the modified electrode, (which is linear in the 0.16 and 1.91 mmol L concentration range), the concentration limit was 0.76 μmol L . In this way, the modified electrode GC/MWCNT/FCo was found to be a promising application for the determination of this neurotransmitter in the area of neuroscience.