Ascites in the Course of Plasma Cell Myeloma Complicated by AL Amyloidosis

A 60-year-old Caucasian male with plasma cell myeloma (PCM) immunoglobulin G (IgG) kappa, International Staging System stage 3, diagnosed 5 months ago, was admitted to the department of hematology due to progression of the disease. He had completed three cycles of chemotherapy comprising bortezomib,...

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Published inTurkish journal of haematology Vol. 35; no. 1; pp. 71 - 72
Main Authors Debski, Jakub, Usnarska-Zubkiewicz, Lidia, Kapelko-Słowik, Katarzyna, Pawluś, Aleksander, Zaleska-Dorobisz, Urszula, Kuliczkowski, Kazimierz
Format Journal Article
LanguageEnglish
Published Turkey Türk Hematoloji Derneği 01.03.2018
Galenos Publishing House
Galenos Publishing
Subjects
Abdomen
amyloidosis
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
ascites
Ascites - pathology
Biopsy
Bone marrow
Chemotherapy
Disease Progression
Fatal Outcome
Hematology
Humans
Hypertension
Images in Hematology
Immunoglobulin Light-chain Amyloidosis - diagnosis
Immunoglobulin Light-chain Amyloidosis - etiology
Immunoglobulin Light-chain Amyloidosis - therapy
Laboratories
Male
Medical prognosis
Middle Aged
Multiple myeloma
Multiple Myeloma - complications
Multiple Myeloma - diagnosis
Multiple Myeloma - therapy
myeloma
Tıp
Tomography, X-Ray Computed
İstanbul
Türkiye
Poland
Kabul Afghanistan
Myeloma
Amyloidosis Ascites
Amiloidoz
Asit
Amyloidosis
Ascites
Miyelom
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Summary:A 60-year-old Caucasian male with plasma cell myeloma (PCM) immunoglobulin G (IgG) kappa, International Staging System stage 3, diagnosed 5 months ago, was admitted to the department of hematology due to progression of the disease. He had completed three cycles of chemotherapy comprising bortezomib, thalidomide, and dexamethasone; one cycle comprising vincristine, doxorubicin, and dexamethasone; and two cycles comprising lenalidomide and dexamethasone, without any clinically significant response. Three weeks before visiting the hospital, the patient also started complaining of progressive weakness, impaired respiratory function, and abdominal distension; an abdominal ultrasound at the time revealed hepatosplenomegaly with ascites, most likely associated with portal hypertension and protein disturbance, which initially he tolerated very well.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ISSN:1300-7777
1308-5263
DOI:10.4274/tjh.2016.0262