Unexpected renal responses in space

Urine output in astronauts following ingestion of an oral water load was low in space on the Russian space station Mir and less than during simulation by 6° head-down bed rest. This surprising observation shows that the effects of gravity and weightlessness on fluid volume regulation are not well un...

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Bibliographic Details
Published inThe Lancet (British edition) Vol. 356; no. 9241; pp. 1577 - 1578
Main Authors Norsk, P, Christensen, NJ, Bie, P, Gabrielsen, A, Heer, M, Drummer, C
Format Journal Article
LanguageEnglish
Published London Elsevier Ltd 04.11.2000
Lancet
Elsevier Limited
Subjects
Adult
Aerospace Medicine
Analysis of Variance
Applied physiology
Astronauts
Bed load
Biological and medical sciences
Gravity effects
Head-Down Tilt
Human physiology applied to population studies and life conditions. Human ecophysiology
Humans
Ingestion
Male
Medical research
Medical sciences
Space life sciences
Transports. Aerospace. Diving. Altitude
Urination - physiology
Urine
Weightlessness
Human
Adult
Astronaut
Renal function
Weightlessness
Space flight disease
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Summary:Urine output in astronauts following ingestion of an oral water load was low in space on the Russian space station Mir and less than during simulation by 6° head-down bed rest. This surprising observation shows that the effects of gravity and weightlessness on fluid volume regulation are not well understood and that the head-down bed-rest model does not simulate the effects of weightlessness on renal water handling.
Bibliography:SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(00)03135-4